Con: High-volume plasma exchange application in nephrology and beyond

Kidney Diseases beyond Nephrology Kidney diseases beyond nephrology—intensive care

The Beginning and Ending Supportive Therapy for the Kidney (BEST Kidney) investigators conducted a multinational, multicentre, prospective, epidemiological survey of acute renal failure (ARF) in intensive care unit (ICU) patients [1], with the intention of determining the association between outcome and different epidemiological parameters: period prevalence of ARF, aetiology, illness severity ...

Nephrology beyond JASN

T hiazolidones are peroxisome proliferator-activated receptor (PPAR ) agonists that enhance insulin sensitivity and are increasingly used as oral antidiabetic agents. The two currently available agents are pioglitazone and rosiglitazone. Their use has dramatically increased recently and this year the results of major outcome trials are expected. Of interest to nephrologists, the thiazolidinedio...

Disaster nephrology: crush injury and beyond.

Disasters result in a substantial number of renal challenges, either by the creation of crush injury in victims trapped in collapsed buildings or by the destruction of existing dialysis facilities, leaving chronic dialysis patients without access to their dialysis units, medications, or medical care. Over the past two decades, lessons have been learned from the response to a number of major nat...

Severe Leptospirosis with Multiple Organ Failure Successfully Treated by Plasma Exchange and High-Volume Hemofiltration

Background. Leptospirosis is a spirochetal zoonosis with complex clinical features including renal and liver failure. Case report. We report the case of a Swiss fisherman presenting with leptospirosis. After initial improvement, refractory septic shock and severe liver and kidney failure developed. The expected mortality was estimated at 90% with clinical scores. The patient underwent plasma ex...

Application of Plasma Exchange in Patients with History of Unexplained Recurrent Abortion: A Case Series